Tuesday, October 12, 2010
High speed Atomic Force Microscopy unveils the steps of Myosin V
In Nature's October issue, the direct visualization of Myosin V motor proteins has been reported by using high-speed atomic force microscopy. The high-resolution movies not only provide corroborative ‘visual evidence’ for previously speculated or demonstrated molecular behaviours, including lever-arm swing, but also reveal more detailed behaviours of the molecules, leading to a comprehensive understanding of the motor mechanism.
Here is the recent report in Nature:
Video imaging of walking myosin V by high-speed atomic force microscopy
Noriyuki Kodera,Daisuke Yamamoto,Ryoki Ishikawa,Toshio Ando, Nature, 2010